VAST Publications - VAST D. rerio (zebrafish)
Morphometric analysis of developing zebrafish embryos allow predicting teratogenicity modes of action in higher vertebrates
Jarque et al.
August 19, 2020
Reproductive Toxicology 96 (2020) 337-348; https://doi.org/10.1016/j.reprotox.2020.08.004
Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/ Cas9-based approach
von der Heyde et al.
July 16, 2020
Sci Rep 10, 11831 (2020). https://doi.org/10.1038/s41598-020-68567-1
TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci
Davis et al.
July 03, 2020
Human Molecular Genetics, , ddaa120, https://doi.org/10.1093/hmg/ddaa120
Integrative discovery of treatments for high-risk neuroblastoma
Almstedt et al.
January 03, 2020
Nat Commun. 2020 Jan 3;11(1):71. doi: 10.1038/s41467-019-13817-8.
The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension
Morikawa et al.
November 12, 2019
Science Signaling 12 Nov 2019: Vol. 12, Issue 607, eaay4430 DOI: 10.1126/scisignal.aay4430
Comparison of Zebrafish Larvae and hiPSC Cardiomyocytes for Predicting Drug-Induced Cardiotoxicity in Humans
Sylvia Dyballa et al.
October 01, 2019
Toxicological Sciences, Volume 171, Issue 2, October 2019, Pages 283–295, https://doi.org/10.1093/toxsci/kfz165
TAF1, associated with intellectual disability in humans, is essential for embryogenesis and regulates neurodevelopmental processes in zebrafish
Gudmundsson et al.
September 01, 2019
Sci Rep. 2019; 9: 10730. Published online 2019 Jul 24. doi: 10.1038/s41598-019-46632-8
Zebrafish larvae as a model system for systematic characterization of drugs and genes in dyslipidemia and atherosclerosis
Bandaru et al.
June 11, 2019
bioRxiv 502674; doi: https://doi.org/10.1101/502674
Bi-allelic Variants in DYNC1I2 Cause Syndromic Microcephaly with Intellectual Disability, Cerebral Malformations, and Dysmorphic Facial Features
Ansar et al.
May 09, 2019
An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos’
Jarque et al.
August 29, 2018
PLOS ONE | https://doi.org/10.1371/journal.pone.0203087 August 29, 2018
An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination
Early et al.
July 06, 2018
DOI: 10.7554/eLife.35136 DOI: 10.7554/eLife.35136
Three-dimensional reconstruction and measurements of zebrafish larvae from high-throughput axial-view in vivo imaging
Guo et al.
April 26, 2017
https://doi.org/10.1364/BOE.8.002611; Received 9 Nov 2016; revised 31 Jan 2017; accepted 31 Jan 2017; published 26 Apr 2017
A truncating mutation in CEP55 is the likely cause of MARCH, a novel syndrome affecting neuronal mitosis.
Frosk et al.
March 06, 2017
J Med Genet. 2017 Mar 6. pii: jmedgenet-2016-104296. doi: 10.1136/jmedgenet-2016-104296. [Epub ahead of print]
SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome
Shaw et al.
January 09, 2017
Nature Genetics (2017) doi:10.1038/ng.3743
De Novo Disruption of the Proteasome Regulatory Subunit PSMD12 Causes a Syndromic Neurodevelopmental Disorder
Kury et al.
January 03, 2017
Developing systems for high-throughput screening of infectious diseases using zebrafish
Veneman, Wouter Jurjen
December 05, 2015
Department of Animal Sciences and Health, Institute of Biology, Faculty of Science, Leiden University
Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type.
Mala Isrie 1,2 et al.
October 14, 2015
Am J Hum Genet. 2015 Dec 3;97(6):790-800. doi: 10.1016/j.ajhg.2015.10.014.
1Center for Human Genetics, University Hospitals Leuven, 3000 Leuven, Belgium; 2Laboratory for Genetics of Cognition, Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium
Semi-automated detection of goitrogenic compounds using transgenic zebrafish embryos and the VAST BioImager platform
SETAC Europe 25th Annual Meeting
Sergio Jarque¹, Eva Fetter², Marek Pípal¹, Marie Smutná¹, Ludek Blaha¹, Stefan Scholz².
May 03, 2015
1RECETOX, Masaryk University, Faculty of Science, Kamenice 753/5, 625 00, Brno
2Department of Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research – UFZ, Permoserstraße 15, 04318 Leipzig, Germany
Establishment and optimization of a high throughput setup to study Staphylococcus epidermidis and Mycobacterium marinum infection as a model for drug discovery.
Veneman WJ¹, Marín-Juez R², de Sonneville J³, Ordas A4, Jong-Raadsen S², Meijer AH4, Spaink HP5.
June 26, 2014
1Institute of Biology, Leiden University; email@example.com. 2ZF-screens BV. 3Life Science Methods BV. 4Institute of Biology, Leiden University. 5Institute of Biology, Leiden University
High-throughput hyperdimensional vertebrate phenotyping
Carlos Pardo-Martin, Amin Allalou, Jaime Medina, Peter M. Eimon, Carolina Wählby Mehmet Fatih Yanik
February 12, 2013
Nature Communications 4, Article number:1467, doi:10.1038/ncomms2475
Presenting VAST BioImager™: A new modular, expandable platform to automate the orientation of 2-7 day old zebrafish larvae for imaging
The Nordic Countries Zebrafish Meeting on the Zebrafish as a model for Development and Disease
Union Biometrica, Geel, Belgium, Union Biometrica, Holliston, MA, USA Yanik lab, MIT, Boston, MA, USA
November 21, 2012
Fully automated cellular-resolution vertebrate screening platform with parallel animal processing
Chang TY, Pardo-Martin C, Allalou A, Wählby C, Yanik MF.
February 01, 2012
Lab Chip. 2012 Feb 21;12(4):711-6. doi: 10.1039/c1lc20849g. Epub 2011 Dec 8.
High-throughput in vivo vertebrate screening.
Pardo-Martin C, Chang TY, Koo BK, Gilleland CL, Wasserman SC, Yanik MF.
August 01, 2010
Nat Methods. 2010 Aug;7(8):634-6. doi: 10.1038/nmeth.1481. Epub 2010 Jul 18.