Union Biometrica, Inc. to Exhibit at the 52nd Midwest Society for Developmental Biology Meeting in St. Louis, MO
VAST BioImager for zebrafish -- Replacing the tedium of manual sample positioning, the VAST BioImager automatically loads each larva into a capillary, positions it laterally, and then rotates it in the field of view of the on-board camera for organ level imaging. Alternately the VAST can be mounted on a high resolution upright (not inverted) microscope for high content bright field or fluorescent imaging at the cellular level. For more detail see: http://www.unionbio.com/vast/
BioSorter flow cytometer --Designed to provide the flexibility for working with samples ranging in sizes from 1 to 1500 microns. This very broad range of sizes includes many interesting types of cells, cell clusters and even whole organisms. We will be available at the meeting to discuss some new applications of the BioSorter, including the use of large delicate cells such as adipocytes and plant protoplasts, cell clusters such as mammalian neurospheres, plant calli and fungal pellets, in addition to cells encapsulated within hydrogel particles. These samples can be analyzed and dispensed intact owing to the low sample pressures, low shear forces and the gentle sorting mechanism. Union Biometrica has developed an autosampler, LP Sampler™ that automatically transfers samples from multiwell plates to the BioSorter for analysis and resorting.
Information regarding the meeting is available at: http://devbio.wustl.edu/MWSDB2014/
About Union Biometrica, Inc.
Large Particle Flow Cytometry for Gentle Sorting of Model Organisms -- Union Biometrica designs and markets tools for high throughput model organism research. This includes many of the model organisms traditionally studied by developmental biologists such as early stages of zebrafish, C.elegans, Drosophila embryos and larvae, sea urchin embryos, Xenopus eggs and embryos, Daphnia, various marine larvae and zooplankton. We provide Large Particle Flow Cytometers (COPAS™ and BioSorter®) for objects that are too large / too fragile for traditional cytometers and offer an alternative to manual sorting. These systems analyze and sort objects based on size and fluorescent parameters. Automating this process offers increased speed, sensitivity, quantification, and repeatability of experiments.
Background publications on the VAST BioImager:
1. Nature Methods, 2010, 7 600-601 and 634-636, Carlos Pardo-Martin, Tsung-Yao Chang, Bryan Kyo Koo, Cody L Gilleland, Steven C Wasserman and Mehmet Fatih Yanik http://www.ncbi.nlm.nih.gov/pubmed/20639868
2. Lab Chip, 2012, 12 711-716, Tsung-Yao Chang, Carlos Pardo-Martin, Amin Allalou, Carolina Wählby and Mehmet Fatih Yanik http://pubs.rsc.org/en/content/articlelanding/2012/lc/c1lc20849g
Publications related to the VAST BioImager can be view at:
- VAST - D. rerio (zebrafish) - http://www.unionbio.com/publications/publication.aspx?id=56
Peer reviewed journal papers referencing our COPAS and BioSorter instruments can be viewed using the link below.
- Flow Cytometry- D. rerio (zebrafish) - http://www.unionbio.com/publications/publication.aspx?id=32
- C. elegans (roundworms) - http://www.unionbio.com/publications/publication.aspx?id=30
- D. melanogaster (fruit fly) - http://www.unionbio.com/publications/publication.aspx?id=31