October 2002 Newsletter, Issue 503
Bead based assays approaching 100,000 compounds / hour with new uHTS screening technique
Diagram of Assay
Principle
In the ongoing quest to accelerate drug discovery, the availability of large combinatorial chemistry libraries is driving the requirement for smarter and higher throughput screening technologies. Assay miniaturization and microtiterplate logistics are two major bottlenecks for increasing assay capacity.
Current uHTS systems can handle up to 200,000 compounds per day.
A poster was recently presented that demonstrates a bead-based flow sorting technique that could dramatically increase the capacity of first line hit selection screening, potentially approaching 100,000 compounds per hour.
Click here to read more about applications or visit:
http://www.unionbio.com/uHTS_bead_COPAS_poster.pdf
NEXT ISSUE: One researcher's use of COPAS to routinely screen a one million member library. CLICK HERE add your name to our list to recieve additional uHTS application notes.
Union Biometrica, Inc. uses SORTED EVENTS NEWSLETTERS to disseminate information about new, innovative techniques for accelerating research through automated sorting techniques designed for small model organisms, combi-chem beads, and other small particles. If you would like more information on products, applications, or customized services on featured techniques or products, please call (617) 591-1211 x11, e-mail: sales@unionbio.com or visit us on the web at http://www.unionbio.com.
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