Sorted Events Newsletter, Issue 503 Automated Analysis & Sorting of Embryonic Stem Cells
A breakthrough method for isolation & optical analysis of embryoid bodies from cultured embryonic stem cells.
Single embryoid body at day 5 in well of a 96-well plate.	While the study of embryoid bodies will provide new insight in developmental biology (cell differentiation, tissue development, and organogenesis), the manual process of isolating the embryoid bodies from cultured embryonic stem cells is time consuming and tedious, thereby, limiting the size and scope of present day experiments. One researcher recently used the COPAS™ instrument from Union Biometrica, Inc. to automate this manual sorting process. Individual embryoid bodies were analyzed and sorted from cultured samples, dispensed into 96-well plates, and raised by methods that resulted in increased differentiation to cardiac cells. CLICK HERE to Read More or visit: http://www.unionbio.com/applications/app_notes/app_embryoidbodies.html
About the instrument: Based on similar priciples as flow cytometry, the COPAS™ instrument from Union Biometrica provides an automated alternative to manual sorting for increased speed, sensitivity, quantification, and repeatability of experiments. The COPAS SELECT instrument analyzes and sorts embryoid bodies and other objects (from 120-300 microns) on the basis of size, density, and fluorescence signals. A gentle pneumatic sorting mechanism is used to permit the analysis and handling of sensitive tissues with a high level of recovery and a low level of lethality. We anticipate that the COPAS instrument will have broad application in embryonic stem cell research, especially in the areas of tissue development and differentiation.
Union Biometrica, Inc. uses "Sorted Events" email newsletters to share information about new, innovative techniques for automated sorting techniques designed for a wide range of applications including: cells, small model organisms, seeds, beads, and other particles (40-1500 microns). For more information, please call (617) 591-1211, e-mail: sales@unionbio.com or visit us on the web at http://www.unionbio.com Union Biometrica, Inc. • 35 Medford Street • Suite 101 • Somerville, MA 02143 • USA
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