2012-05-15T14:09:46Z Union Biometrica http://www.unionbio.com/feeds/publications.xml Copyright 2010 Union Biometrica http://www.unionbio.com/publications/detail.aspx?id=6 2012-04-30T04:00:00Z

The reprogramming of somatic cells into human induced pluripotent stem cells (iPS cells) has opened unique perspectives for producing disease and patient specific human cell products. To take full advantage of this technology there is a need to produce a high number of iPS cell lines using high throughput techniques, to standardize the respective protocols and to deliver fully characterized cells. Union Biometrica’s large particle flow cytometry technology (COPAS and BioSorter) allows the analysis and sorting of intact hiPS cell clusters based on size, optical density and fluorescent parameters. Recent experiments by Wanek & Zenke (Institute for Biomedical Engineering - Cell Biology, RWTH Aachen, Germany) demonstrate that the COPAS PLUS HTS can be used to analyze and sort primary human induced pluripotent stem cell colonies. The instrument can analyze accurately and sort similar cell clusters from a complex mixture of varying sizes. This process is gentle and does not influence the morphology or viability compared to manually sorted cell clusters. Additionally, the Profiler II allows discriminating clusters with full fluorescence from those with partial fluorescence labeling.

http://www.unionbio.com/publications/detail.aspx?id=5 2012-04-11T04:00:00Z http://www.unionbio.com/publications/detail.aspx?id=4 2012-02-29T05:00:00Z

Expand the Capability of Your System by Mapping Fluorescence Positional Information